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    Fiona Fuchs - Model page

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    They devised methods to mark and track the behavior of these tumor-initiating stem cells and discovered that not only are these cells at invasive fronts of the cancers, but they are also responsible for tumor relapse following chemo- and immune-therapies administered to mice with tumors.

    By dissecting the underlying mechanisms, performing high-throughput functional screens for oncogenes and tumor suppressors in mice, and relating their findings to humans, Fuchs hopes her research will lead to new therapeutic approaches that target the cancerous stem cells without affecting tissue stem cells.

    Overall, Fuchs studies tissue biology at multiple levels, from its stem cells and the signals that control them to the epigenetic, transcriptional, and translational programs that maintain an orchestrated balance of tissue growth.

    Fuchs is a faculty member in the David Rockefeller Graduate Program , the Tri-Institutional M. Program , and the Tri-Institutional Ph. Assistant Professor, — Associate Professor, — Professor, — University of Chicago.

    Associate Investigator, — Investigator, — Howard Hughes Medical Institute. National Academy of Sciences National Academy of Medicine American Academy of Arts and Sciences American Philosophical Society Fellow, American Association for the Advancement of Science Associate Member, European Molecular Biology Organization Foreign Member, The Royal Society.

    Quiroz, F. Liquid-liquid phase separation drives skin barrier formation. Science , eaax Gur-Cohen, S. Stem cell-driven lymphatic remodeling coordinates tissue regeneration.

    Science , — Ellis, S. Distinct modes of cell competition shape mammalian tissue morphogenesis. Einen Gegenpol. Ich will zeigen, dass ich erwachsen geworden bin.

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    COVID is an emerging, rapidly evolving situation. FDAAA and the Final Rule How to Apply for a PRS Account How to Register Your Study How to Edit Your Study Record How to Submit Your Results Frequently Asked Questions Support Materials Training Materials Resources Selected Publications Clinical Alerts and Advisories RSS Feeds Trends, Charts, and Maps Downloading Content for Analysis About Site What's New ClinicalTrials.

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    Home Search Results Study Record Detail Saved Studies. Save this study. Warning You have reached the maximum number of saved studies A Study to Investigate Atezolizumab and Chemotherapy Compared With Placebo and Chemotherapy in the Neoadjuvant Setting in Participants With Early Stage Triple Negative Breast Cancer IMpassion The safety and scientific validity of this study is the responsibility of the study sponsor and investigators.

    Listing a study does not mean it has been evaluated by the U. Federal Government. Read our disclaimer for details. Last Update Posted : October 22, Study Details Tabular View No Results Posted Disclaimer How to Read a Study Record.

    Study Description. This is a global Phase III, double-blind, randomized, placebo-controlled study designed to evaluate the efficacy and safety of neoadjuvant treatment with atezolizumab anti-programmed death-ligand 1 [anti-PD-L1] antibody and nab-paclitaxel followed by doxorubicin and cyclophosphamide nab-pac-AC , or placebo and nab-pac-AC in participants eligible for surgery with initial clinically assessed triple-negative breast cancer TNBC.

    Drug Information available for: Atezolizumab. FDA Resources. Arms and Interventions. Atezolizumab will be administered as per schedule described in respective arm.

    Nab-paclitaxel will be administered as per schedule described in the arms. Doxorubicin will be administered as per schedule described in the arms.

    Cyclophosphamide will be administered as per schedule described in the arms. Filgrastim will be administered according to local prescribing information as determined by the Investigator for 4 doses after completion of initial 12 weeks.

    Pegfilgrastim will be administered according to local prescribing information as determined by the Investigator for 4 doses after completion of initial 12 weeks.

    Placebo matched to atezolizumab will be administered as per schedule described in respective arm. Cited by. Back to tab navigation Download options Please wait Supplementary information PDF K.

    Download Citation. Request permissions. Rational synthesis of epoxy-functional spheres, worms and vesicles by RAFT aqueous emulsion polymerisation of glycidyl methacrylate F.

    Hatton, M. Derry and S. Armes, Polym. For reproduction of material from NJC: [Original citation] - Published by The Royal Society of Chemistry RSC on behalf of the Centre National de la Recherche Scientifique CNRS and the RSC.

    For reproduction of material from PCCP: [Original citation] - Published by the PCCP Owner Societies. For reproduction of material from PPS: [Original citation] - Published by The Royal Society of Chemistry RSC on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC.

    For reproduction of material from all other RSC journals: [Original citation] - Published by The Royal Society of Chemistry.

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